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Sep 27, 2024
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HTH RS M *733 / Statistical and Methodologic Issues in Randomized Clinical Trials3 unit(s)
This course will consider important statistical issues relating to the design, analysis and interpretation of randomized clinical trials. Specific topics will include issues in sample size determination, large simple trials, factorial designs, cluster randomization, cross-over trials, missing data in RCTs, meta-analysis, non-inferiority trials, subgroup analysis, composite outcomes in RCTs, stopping rules, cost-effectiveness analysis, statistical analysis of costeffectiveness data, survival analysis and repeated measures in RCTs.
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