HTH RS M 777 / Methods of Diagnostic and Prognostic Research

3 unit(s)

Prerequisite(s): HTH RS M 721 and HTH RS M 702 or permission of the instructor

This is an advanced course in diagnostic and prognostic test methodology and statistical analysis. For diagnostic testing we will discuss phases of test development, basic and advanced study designs, methodological issues related to choice of population and test verification. In prognostic research we will discuss overall prognosis, risk factor research, prediction modeling, and stratified medicine. For both diagnosis and prognosis research, we will consider issues in performing systematic reviews and formulating guidelines.